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Title:Cryo-EM reconstruction of yeast 80S ribosome in complex with mRNA, tRNA and eEF2 (GMPPCP/sordarin)
Authors:Pellegrino S, Demeshkina N, Mancera-Martinez E, Melnikov S, Simonetti A, Myasnikov A, Yusupov M, Yusupova G, Hashem Y
Sample:80S ribosome in complex with mRNA, tRNA and eEF2 in presence of non-hydrolizable GTP (GMPPCP) and anti-fungal drug (sordarin)
Method:Single particle reconstruction (4.4 angstroms resolution)
Red flagLatest update:2018-08-08
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Summary
Status: Released
Deposition date: 2018-06-07
Deposition site: PDBe
Processing site: PDBe
Header release date: 2018-07-11
Map release date: 2018-07-11
Primary citation: Structural Insights into the Role of Diphthamide on Elongation Factor 2 in mRNA Reading-Frame Maintenance.
Pellegrino S, Demeshkina N, Mancera-Martinez E, Melnikov S, Simonetti A, Myasnikov A, Yusupov M, Yusupova G, Hashem Y
J. Mol. Biol. (2018) 430, pp. 2677-2687 [PubMed 29886014] [DOI]
Sample: 80S ribosome in complex with mRNA, tRNA and eEF2 in presence of non-hydrolizable GTP (GMPPCP) and anti-fungal drug (sordarin)
Resolution: 4.4 Å (determined by FSC 0.143 CUT-OFF)
Fitted PDB:
PDB Authors PubMed Status
6gq1Pellegrino, S., Demeshkina, N., Mancera-Martinez, E., Melnikov, S., Simonetti, A., Myasnikov, A., Yusupov, M., Yusupova, G., Hashem, Y.29886014Released