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Title:Imidazoleglycerol-phosphate dehydratase
Authors:Rawson S, Bisson C
Sample:Imidazoleglycerol-phosphate dehydratase (IGPD2) in complex with triazole-phosphonate inhibitor (C384)
Method:Single particle reconstruction (3.1 angstroms resolution)
Red flagLatest update:2018-02-28
Other Views:
Status: Released
Deposition date: 2017-11-15
Deposition site: PDBe
Processing site: PDBe
Header release date: 2017-11-29
Map release date: 2018-02-07
Primary citation: Elucidating the structural basis for differing enzyme inhibitor potency by cryo-EM.
Rawson S, Bisson C, Hurdiss DL, Fazal A, McPhillie MJ, Sedelnikova SE, Baker PJ, Rice DW, Muench SP
Proc. Natl. Acad. Sci. U.S.A. (2018) 115, pp. 1795-1800 [PubMed 29434040] [DOI]
Sample: Imidazoleglycerol-phosphate dehydratase (IGPD2) in complex with triazole-phosphonate inhibitor (C384)
Resolution: 3.1 Å (determined by FSC 0.143 CUT-OFF)
Fitted PDB:
PDB Authors PubMed Status
6ezjRawson, S., Bisson, C., Hurdiss, D.L., Muench, S.P.29434040Released