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Title:Cryo-EM structure of human insulin degrading enzyme in complex with insulin
Authors:Zhang Z, Liang WG, Bailey LJ, Tan YZ, Wei H, Kossiakoff AA, Carragher B, Potter SC, Tang WJ
Sample:Insulin degrading enzyme/Insulin
Method:Single particle reconstruction (3.7 angstroms resolution)
Red flagLatest update:2018-07-18
Other Views:
Status: Released
Deposition date: 2017-09-22
Deposition site: RCSB
Processing site: RCSB
Header release date: 2017-11-22
Map release date: 2017-11-22
Primary citation: Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
Zhang Z, Liang WG, Bailey LJ, Tan YZ, Wei H, Wang A, Farcasanu M, Woods VA, McCord LA, Lee D, Shang W, Deprez-Poulain R, Deprez B, Liu DR, Koide A, Koide S, Kossiakoff AA, Li S, Carragher B, Potter CS, Tang WJ
Elife (2018) 7 [PubMed 29596046] [DOI]
Sample: Insulin degrading enzyme/Insulin
Resolution: 3.7 Å (determined by FSC 0.143 CUT-OFF)
Fitted PDB:
PDB Authors PubMed Status
6b3qLiang, W.G., Zhang, Z., Bailey, L.J., Kossiakoff, A.A., Tan, Y.Z., Wei, H., Carragher, B., Potter, S.C., Tang, W.J.29596046Released